Better Classification of Respiratory Amyloidosis

ID studio #: NCT05862961

condizione: amiloidosi

stato: Non ancora reclutamento

The B-AR project is based on a retrospective analysis of amyloidosis typing and the identification of their amylogenic protein.This work should be able to unite many clinicians, including pulmonologists and pathologists around a rare disease that still suffers from insufficient data.

risultati: https://clinicaltrials.gov/ct2/show/results/NCT05862961

ultimo aggiornamento: Dicembre 28, 2023

taglia / iscrizione: 70

descrizione dello studio: The B-AR study will highlight the interest of proteomic analysis of amyloidosis compared to their identification by immunostaining. The objective is to reduce diagnostic wandering and to improve patient management. The typing of respiratory amyloidosis will allow a better characterization of the disease and thus, to propose a dedicated therapeutic management.

risultati primari:

• Number of cases with identification of the amylogenic protein in respiratory amyloidosis.
  Identification of amylogenic protein by Proteomic Analysis Based on Tandem Mass Spectrometry on histological sample of the tracheobronchial or pulmonary tree.
• 1 day (at inclusion)
  

risultati secondari:

• Distribution and severity of amyloidosis
  1 day (at inclusion)

criterio di inclusione:

criteri di esclusione: criteri:

Subject receiving state medical aid
Subject deprived of freedom, or under a legal protective measure (example: patients under guardianship or curators)

sedi dei centri di prova: